The Science

Combining two established concepts has led to a revolutionary daytime therapy

Two independently proven concepts:

  1. Research has shown that patients with OSA have a genioglossus (tongue) that is stronger, but exhibits less endurance, than those without OSA1.
  2. Neuromuscular electrical stimulation (NMES) of skeletal muscles is associated with an improvement of muscle endurance2-3.

Combining the two research areas introduces a new approach to sleep disturbance: NMES applied to the tongue as a patient friendly daytime therapy helping solve a root problem of sleep apnea and snoring.

The clinical story to eXciteOSA started in 2018. Watch the video for more on the science behind eXciteOSA. To learn more, feel free to contact us directly. Or, to understand how eXciteOSA may help you, click on our Consult a Physician and we will direct you to a local expert or a physician online.

Clinically Proven

Multiple studies demonstrate efficacy across a broad group of patients4-5

The clinical evidence on eXciteOSA® shows an improvement in quality of sleep by reducing snoring and sleep apnea when used for 20 minutes, once a day for 6 weeks 4-5

79%
of sleep apnea patients
achieved reduction in
objective OSA measures5
89%
of bed partners reported
reduction of their partners
snoring4
90%
of patients experienced
reduction in objectively-measured snoring time4

Trusted by Experts

Backed by leading sleep specialists

“We believe that eXciteOSA® therapy will be able to help many patients in the near future.”

— Dr. Marina Carrasco-Llatas

  • Specialist in ORL at Dr. Peset University Hospital, Valencia, Spain
  • Expert in Sleep Medicine
  • President of the Commission on Roncopathy and Sleep Apnoea of the Spanish Society of Otolaryngology and Head and Neck Surgery
Atul Malhotra

“I am optimistic that this treatment will be an important treatment approach for patients with with mild sleep apnea and snoring.”

— Professor Atul Malhotra

  • M.D. Research Chief, Pulmonary, Critical Care and Sleep Medicine
  • Peter C. Farrell Presidential Chair and Professor in Respiratory Medicine
  • Former President, American Thoracic Society 2015- 2016

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References

  1. Eckert DJ, Lo YL, Saboisky JP, Jordan AS, White DP, Malhotra A. Sensorimotor function of the upper-airway muscles and respiratory sensory processing in untreated obstructive sleep apnea. J Appl Physiol 2011;111:1644-1653
  2. Nuhr M, Crevenna R, Gohlsch B, Bittner C, Pleiner J, Wiesinger G, Fialka-Moser V, Quittan M, Pette D. Functional and biochemical properties of chronically stimulated human skeletal muscle. Eur J Appl Physiol 2003;89:202-208
  3. Gondin J, Brocca L, Bellinzona E, D’Antona G, Maffiuletti NA, Miotti D, Pellegrino MA, Bottinelli R. Neuromuscular electrical stimulation training induces atypical adaptations of the human skeletal muscle phenotype: a functional and proteomic analysis. J Appl Physiol 2011;110:433-450
  4. Baptista PM, Martinez Ruiz de Apodaca P, Carrasco M, Fernandez S, Wong PY, Zhang H, Hassaan A, Kotecha B. Daytime neuromuscular electrical therapy of tongue muscles in improving snoring in individuals with primary snoring and mild obstructive sleep apnea. J Clin Med 2021;10:1-11
  5. Based on analysis of n=65 participants with mild OSA recruited from multiple UK and European sites, who underwent a single-arm trial of eXciteOSA for a duration of six weeks between February 2019 and April 2020. Data on file.